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Hyperoxic Reperfusion after Global Cerebral Ischemia Promotes Inflammation and Long-Term Hippocampal Neuronal Death

In this study we tested the hypothesis that long-term neuropathological outcome is worsened by hyperoxic compared to normoxic reperfusion in a rat global cerebral ischemia model. Adult male rats were anesthetized and subjected to bilateral carotid arterial occlusion plus bleeding hypotension for 10 ...

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Autori principali: Hazelton, Julie L., Balan, Irina, Elmer, Greg I., Kristian, Tibor, Rosenthal, Robert E., Krause, Gary, Sanderson, Thomas H., Fiskum, Gary
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867550/
https://ncbi.nlm.nih.gov/pubmed/20059303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.1186
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