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Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet

An acute injection of brain-derived neurotrophic factor (BDNF) in the hypothalamic paraventricular nucleus (PVN) reduces body weight by decreasing feeding and increasing energy expenditure (EE), in animals on standard laboratory chow. Animals have divergent responses to a high-fat diet (HFD) exposur...

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Détails bibliographiques
Auteurs principaux: Wang, ChuanFeng, Godar, Rebecca J., Billington, Charles J., Kotz, Catherine M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867522/
https://ncbi.nlm.nih.gov/pubmed/20164202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00844.2009
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