Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

Prolonged endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) have been linked to apoptosis via several mechanisms, including increased expression of C/EBP homologous protein (Chop). Increased long-chain fatty acids, in particular saturated fatty acids, induce ER...

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Detaylı Bibliyografya
Asıl Yazarlar: Pfaffenbach, Kyle T., Gentile, Christopher L., Nivala, Angela M., Wang, Dong, Wei, Yuren, Pagliassotti, Michael J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867372/
https://ncbi.nlm.nih.gov/pubmed/20159858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00642.2009
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