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Effect of 11β-hydroxysteroid dehydrogenase-1 inhibition on hepatic glucose metabolism in the conscious dog

Inactive cortisone is converted to active cortisol within the liver by 11β-hydroxysteroid dehydrogenase-1 (11β-HSD1), and impaired regulation of this process may be related to increased hepatic glucose production (HGP) in individuals with type 2 diabetes. The primary aim of this study was to investi...

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Main Authors: Edgerton, Dale S., Basu, Rita, Ramnanan, Christopher J., Farmer, Tiffany D., Neal, Doss, Scott, Melanie, Jacobson, Peer, Rizza, Robert A., Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867371/
https://ncbi.nlm.nih.gov/pubmed/20159854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00740.2009
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