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A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats
Tissue macrophage inflammatory pathways contribute to obesity-associated insulin resistance. Here, we have examined the efficacy and mechanisms of action of a novel anti-inflammatory compound (HE3286) in vitro and in vivo. In primary murine macrophages, HE3286 attenuates LPS- and TNFα-stimulated inf...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867370/ https://ncbi.nlm.nih.gov/pubmed/20159859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00668.2009 |
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