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Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism.

We investigated whether transforming growth factor alpha (TGF-alpha) is involved in hepatocyte growth responses both in vivo and in culture. During liver regeneration after partial hepatectomy in rats, TGF-alpha mRNA increased; it reached a maximum (approximately 9-fold higher than normal) at the pe...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Mead, J E, Fausto, N
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1989
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2922399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.5.1558
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