Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

Microcephaly affects ∼1% of the population and is associated with mental retardation, motor defects and, in some cases, seizures. We analyzed the mechanisms underlying brain size determination in a mouse model of human microcephaly. The Hertwig's anemia (an) mutant shows peripheral blood cytope...

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Autors principals: Lizarraga, Sofia B., Margossian, Steven P., Harris, Marian H., Campagna, Dean R., Han, An-Ping, Blevins, Sherika, Mudbhary, Raksha, Barker, Jane E., Walsh, Christopher A., Fleming, Mark D.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867323/
https://ncbi.nlm.nih.gov/pubmed/20460369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.040410
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