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LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos
Cortical pulling on astral microtubules positions the mitotic spindle in response to PAR polarity cues and G protein signaling in many systems. In Caenorhabditis elegans single-cell embryos, posterior spindle displacement depends on Gα and its regulators GPR-1/2 and LIN-5. GPR-1/2 and LIN-5 are nece...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867312/ https://ncbi.nlm.nih.gov/pubmed/20421425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001115 |
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