The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma

Peripheral T cell lymphomas (PTCLs) are highly aggressive malignancies with poor prognosis. Their molecular pathogenesis is not well understood and small animal models for the disease are lacking. Recently, the chromosomal translocation t(5;9)(q33;q22) generating the interleukin-2 (IL-2)–inducible T...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Pechloff, Konstanze, Holch, Julian, Ferch, Uta, Schweneker, Marc, Brunner, Kristina, Kremer, Markus, Sparwasser, Tim, Quintanilla-Martinez, Leticia, Zimber-Strobl, Ursula, Streubel, Berthold, Gewies, Andreas, Peschel, Christian, Ruland, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867290/
https://ncbi.nlm.nih.gov/pubmed/20439541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092042
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados