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Muscle Wasting and Interleukin-6-Induced Atrogin-I Expression in the Cachectic Apc(Min/+) Mouse

Interleukin-6 (IL-6) is necessary for cachexia in Apc(Min/+) mice, but the mechanisms inducing this myofiber wasting have not been established. The purpose of this study was to examine gastrocnemius muscle wasting in the Apc(Min/+) mouse and to determine IL-6 regulated mechanisms contributing to mus...

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Detalhes bibliográficos
Main Authors: Baltgalvis, Kristen A., Berger, Franklin G., Peña, Maria Marjorette O., Davis, J. Mark, White, James P., Carson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867110/
https://ncbi.nlm.nih.gov/pubmed/18712412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0574-6
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