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Cysteine-free rop: A four-helix bundle core mutant has wild-type stability and structure but dramatically different unfolding kinetics

Cysteine residues can complicate the folding and storage of proteins due to improper formation of disulfide bonds or oxidation of residues that are natively reduced. Wild-type Rop is a homodimeric four-helix bundle protein and an important model for protein design in the understanding of protein sta...

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Detalhes bibliográficos
Main Authors: Hari, Sanjay B, Byeon, Chang, Lavinder, Jason J, Magliery, Thomas J
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867008/
https://ncbi.nlm.nih.gov/pubmed/20095056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.342
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