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Low density of sodium channels supports action potential conduction in axons of neonatal rat optic nerve.
The density of sodium channels in premyelinated axons was estimated from measurements of the binding of [3H]saxitoxin to neonatal rat optic nerve. The maximum saturable binding capacity of the nerve was 16.2 +/- 1.2 fmol/mg of wet weight, with an equilibrium dissociation constant of 0.88 +/- 0.18 nM...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2537496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.4.1406 |
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