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NGFI-B targets mitochondria and induces cardiomyocyte apoptosis in restraint-stressed rats by mediating energy metabolism disorder

NGFI-B/Nur77/TR3, originally identified as an immediate-early gene rapidly induced by serum and growth factors, is a member of the steroid hormone nuclear receptor superfamily with no identified endogenous ligand. NGFI-B induces apoptosis in a number of cell lineages exposed to proapoptotic stimuli...

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Detalhes bibliográficos
Main Authors: Wang, XinXing, Liu, XiaoHua, Kong, RuiRui, Zhan, Rui, Wang, XiaoMing, Leng, Xue, Gong, JingBo, Duan, Meng, Wang, LiQun, Wu, Lei, Qian, LingJia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866952/
https://ncbi.nlm.nih.gov/pubmed/19412742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-009-0116-y
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