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A Novel Link to Base Excision Repair
DNA interstrand crosslinks (ICLs) can arise from reactions with endogenous chemicals, such as the lipid peroxidation product malondialdehyde, or from exposure to a variety of clinical anti-cancer drugs, most notably bifunctional alkylators and platinum compounds. Because they covalently link the two...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866823/ https://ncbi.nlm.nih.gov/pubmed/20172733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.01.003 |
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