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Regulation of EGFR and Notch signaling by distinct isoforms of D-cbl during Drosophila development

Cells receive and interpret extracellular signals to regulate cellular responses such as proliferation, cell survival and differentiation. However, proper inactivation of these signals is critical for appropriate homeostasis. Cbl proteins are E3-ubiquitin ligases that restrict receptor tyrosine kina...

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Main Authors: Wang, Yuan, Chen, Zhihong, Bergmann, Andreas
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866751/
https://ncbi.nlm.nih.gov/pubmed/20302857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.03.005
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