Heme Oxygenase-2 Modulates Early Pathogenesis after Traumatic Injury to the Immature Brain

We determined if heme oxygenase-2 (HO-2), an enzyme that degrades the pro-oxidant heme, confers neuroprotection in the developing brain after traumatic brain injury (TBI). Male HO-2 wild-type (WT) and homozygous knockout (KO) mice at postnatal day 21 were subjected to TBI and euthanized 1, 7, and 14...

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Bibliografske podrobnosti
Main Authors: Yoneyama-Sarnecky, Tomoko, Olivas, Andrea D., Azari, Soraya, Ferriero, Donna M., Manvelyan, Hovhannes M., Noble-Haeusslein, Linda J.
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2010
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866583/
https://ncbi.nlm.nih.gov/pubmed/20389079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000258700
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