Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells.

The highly conserved interferon (IFN)-stimulated regulatory elements of the human genes 6-16 and 9-27 bind to one or more proteins (E factor) detected in extracts of human Bristol 8 B cells or human foreskin fibroblast cells treated with IFN-alpha. E factor is not detectable in extracts of untreated...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Dale, T C, Imam, A M, Kerr, I M, Stark, G R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2919169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.4.1203
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