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Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells.

The highly conserved interferon (IFN)-stimulated regulatory elements of the human genes 6-16 and 9-27 bind to one or more proteins (E factor) detected in extracts of human Bristol 8 B cells or human foreskin fibroblast cells treated with IFN-alpha. E factor is not detectable in extracts of untreated...

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Autors principals: Dale, T C, Imam, A M, Kerr, I M, Stark, G R
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC286654/
https://ncbi.nlm.nih.gov/pubmed/2919169
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