Pyrroline-5-carboxylate synthase and proline biosynthesis: From osmotolerance to rare metabolic disease

Pyrroline-5-carboxylate synthase (P5CS) is a bifunctional enzyme that exhibits glutamate kinase (GK) and γ-glutamyl phosphate reductase (GPR) activities. The enzyme is highly relevant in humans because it belongs to a combined route for the interconversion of glutamate, ornithine and proline. The de...

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Bibliografske podrobnosti
Main Authors: Pérez-Arellano, Isabel, Carmona-Álvarez, Francisco, Martínez, Ana I, Rodríguez-Díaz, Jesús, Cervera, Javier
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2010
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866264/
https://ncbi.nlm.nih.gov/pubmed/20091669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.340
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