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Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens.

Platelet-derived growth factor (PDGF) has been implicated in several nonmalignant pathophysiological processes, including proliferative diseases of the kidney. Glomerular mesangial cells secrete a PDGF-like factor and express the PDGF A-chain and c-sis (or B-chain) mRNAs. We report here that both mR...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Silver, B J, Jaffer, F E, Abboud, H E
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.1056
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