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Alternative splicing of HLA-DQB transcripts and secretion of HLA-DQ beta-chain proteins: allelic polymorphism in splicing and polyadenylylation sites.

HLA class II antigens are highly polymorphic cell-surface proteins involved in initiation and regulation of the immune response. Allelic sequence variation primarily affects the structure of the first external domains of alpha and beta component chains. Here we provide evidence for other types of al...

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Autores principales: Briata, P, Radka, S F, Sartoris, S, Lee, J S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC286609/
https://ncbi.nlm.nih.gov/pubmed/2464826
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