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Structural Characterization of Formaldehyde-induced Cross-links Between Amino Acids and Deoxynucleosides and Their Oligomers

Exposure to formaldehyde results in the formation of DNA-protein cross-links (DPCs) as a primary genotoxic effect. Although DPCs are biologically important and eight amino acids have been reported to form stable adducts with formaldehyde, the structures of these cross-links have not yet been elucida...

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Detalhes bibliográficos
Main Authors: Lu, Kun, Ye, Wenjie, Zhou, Li, Collins, Leonard B., Chen, Xian, Gold, Avram, Ball, Louise M, Swenberg, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866014/
https://ncbi.nlm.nih.gov/pubmed/20178313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908282f
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