Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation.

Structurally distinguishable mutants of human epidermal growth factor receptor (EGFR) were used to investigate the mechanism of EGFR autophosphorylation. Mutant receptors generated by site-directed mutagenesis were expressed in transfected NIH 3T3 cells lacking endogenous receptors. After coincubati...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Honegger, A M, Kris, R M, Ullrich, A, Schlessinger, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2915986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.925
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