Functional Amyloids as Natural Storage of Peptide Hormones in Pituitary Secretory Granules

Amyloids are highly organized cross β-sheet-rich protein or peptide aggregates that are associated with pathological conditions including Alzheimer’s disease and type II diabetes. However, amyloids may also have a normal biological function as demonstrated by fungal prions, which are involved in pri...

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Auteurs principaux: Maji, Samir K., Perrin, Marilyn H., Sawaya, Michael R., Jessberger, Sebastian, Vadodaria, Krishna, Rissman, Robert A., Singru, Praful S., Nilsson, K Peter R, Simon, Rozalyn, Schubert, David, Eisenberg, David, Rivier, Jean, Sawchenko, Paul, Vale, Wylie, Riek, Roland
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865899/
https://ncbi.nlm.nih.gov/pubmed/19541956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1173155
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