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pH-Sensitive Mebeverine Microspheres for Colon Delivery
Mebeverine hydrochloride is known to suffer from extensive first pass effect. In an attempt to improve its oral bioavailability and possibility to restrict its absorption only to the colon, mebeverine microspheres were prepared by emulsion solvent evaporation method. Four formulations were prepared...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865826/ https://ncbi.nlm.nih.gov/pubmed/20502560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.57303 |
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