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Synthesis and Antiviral Studies of Novel N-Sulphonamidomethyl piperazinyl Fluoroquinolones

A series of novel N-Sulphonamidomethyl piperzinyl fluoroquinolones were synthesized and screened antiviral activity. Eight compounds were synthesized through modifying the N(4)-hydrogen of piperazine in fluoroquinolones with formaldehyde and sulphanomides by Mannich reactions. The structures of the...

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Библиографические подробности
Главные авторы: Selvam, P., Rathore, P., Karthikumar, S., Velkumar, K., Palanisamy, P., Vijayalakhsmi, S., Witvrouw, M.
Формат: Artigo
Язык:Inglês
Опубликовано: Medknow Publications 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865816/
https://ncbi.nlm.nih.gov/pubmed/20502550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.57293
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