A GREM1 Gene Variant Associates with Diabetic Nephropathy

Gremlin, a cell growth and differentiation factor, promotes the development of diabetic nephropathy in animal models, but whether GREM1 gene variants associate with diabetic nephropathy is unknown. We comprehensively screened the 5` upstream region (including the predicted promoter), all exons, intr...

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Главные авторы: McKnight, Amy Jayne, Patterson, Christopher C., Pettigrew, Kerry A., Savage, David A., Kilner, Jill, Murphy, Madeline, Sadlier, Denise, Maxwell, Alexander P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2010
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865734/
https://ncbi.nlm.nih.gov/pubmed/20150533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070773
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