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Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins
Site-directed spin labeling (SDSL) was used to investigate local structure and conformational exchange in two bacterial outer-membrane TonB-dependent transporters, BtuB and FecA. Protecting osmolytes, such as polyethylene glycols (PEGs) are known to modulate a substrate-dependent conformational equi...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865716/ https://ncbi.nlm.nih.gov/pubmed/20014029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.305 |
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