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Elucidating residue roles in engineered variants of AraC regulatory protein

The AraC regulatory protein was previously engineered to control gene expression specifically in response to d-arabinose and not the native effector l-arabinose (Tang et al., J Am Chem Soc 2008;130:5267–5271). Mutations were targeted in the ligand-binding pocket and on the AraC N-terminal arm, which...

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Detalhes bibliográficos
Main Authors: Tang, Shuang-Yan, Cirino, Patrick C
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865714/
https://ncbi.nlm.nih.gov/pubmed/20014443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.310
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