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DNA binding specificity of the Arc and Mnt repressors is determined by a short region of N-terminal residues.

The Arc and Mnt repressors of phage P22 are related proteins that bind to different operator DNA sites. By creating a hybrid Arc-Mnt protein, we show that the binding specificity of Mnt can be switched to that of Arc by replacing six residues at the N terminus of Mnt with the corresponding nine resi...

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Détails bibliographiques
Auteurs principaux: Knight, K L, Sauer, R T
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC286564/
https://ncbi.nlm.nih.gov/pubmed/2644643
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