DNA binding specificity of the Arc and Mnt repressors is determined by a short region of N-terminal residues.
The Arc and Mnt repressors of phage P22 are related proteins that bind to different operator DNA sites. By creating a hybrid Arc-Mnt protein, we show that the binding specificity of Mnt can be switched to that of Arc by replacing six residues at the N terminus of Mnt with the corresponding nine resi...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1989
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2644643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.797 |
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