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Concomitant Duplications of Opioid Peptide and Receptor Genes before the Origin of Jawed Vertebrates

BACKGROUND: The opioid system is involved in reward and pain mechanisms and consists in mammals of four receptors and several peptides. The peptides are derived from four prepropeptide genes, PENK, PDYN, PNOC and POMC, encoding enkephalins, dynorphins, orphanin/nociceptin and beta-endorphin, respect...

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Bibliografske podrobnosti
Main Authors: Sundström, Görel, Dreborg, Susanne, Larhammar, Dan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865548/
https://ncbi.nlm.nih.gov/pubmed/20463905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010512
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