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DNA Adenine Methylation Is Required to Replicate Both Vibrio cholerae Chromosomes Once per Cell Cycle

DNA adenine methylation is widely used to control many DNA transactions, including replication. In Escherichia coli, methylation serves to silence newly synthesized (hemimethylated) sister origins. SeqA, a protein that binds to hemimethylated DNA, mediates the silencing, and this is necessary to res...

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Autori principali: Demarre, Gaëlle, Chattoraj, Dhruba K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865523/
https://ncbi.nlm.nih.gov/pubmed/20463886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000939
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