The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues

BACKGROUND: Expansion of multi-C2H2 domain zinc finger (ZNF) genes, including the Krüppel-associated box (KRAB) subfamily, paralleled the evolution of tetrapodes, particularly in mammalian lineages. Advances in their cataloging and characterization suggest that the functions of the KRAB-ZNF gene fam...

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Autors principals: Lorenz, Peter, Dietmann, Sabine, Wilhelm, Thomas, Koczan, Dirk, Autran, Sandra, Gad, Sophie, Wen, Gaiping, Ding, Guohui, Li, Yixue, Rousseau-Merck, Marie-Françoise, Thiesen, Hans-Juergen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865497/
https://ncbi.nlm.nih.gov/pubmed/20346131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-206
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