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Comparative analysis of right element mutant lox sites on recombination efficiency in embryonic stem cells
BACKGROUND: Cre-mediated site-specific integrative recombination in mouse embryonic stem (ES) cells is a useful tool for genome engineering, allowing precise and repeated site-specific integration. To promote the integrative reaction, a left element/right element (LE/RE) mutant strategy using a pair...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865440/ https://ncbi.nlm.nih.gov/pubmed/20356367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-29 |
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