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Creating novel proteins by combining design and selection
We present the results of combining design and selection to remodel a protein–peptide binding interface, using the peptide PTIEEVD and the TPR1 module interaction as our test case. We initially used the program Rosetta to interrogate possible TPR1 sequences compatible with binding the peptide PTIEEV...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865361/ https://ncbi.nlm.nih.gov/pubmed/20304973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq015 |
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