Protein Complex of Drosophila ATRX/XNP and HP1a Is Required for the Formation of Pericentric Beta-heterochromatin in Vivo

ATRX belongs to the family of SWI2/SNF2-like ATP-dependent nucleosome remodeling molecular motor proteins. Mutations of the human ATRX gene result in a severe genetic disorder termed X-linked α-thalassemia mental retardation (ATR-X) syndrome. Here we perform biochemical and genetic analyses of the D...

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Autores principales: Emelyanov, Alexander V., Konev, Alexander Y., Vershilova, Elena, Fyodorov, Dmitry V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865330/
https://ncbi.nlm.nih.gov/pubmed/20154359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064790
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