Biochemical Characterization of κM-RIIIJ, a Kv1.2 Channel Blocker: EVALUATION OF CARDIOPROTECTIVE EFFECTS OF κM-CONOTOXINS

Conus snail (Conus) venoms are a valuable source of pharmacologically active compounds; some of the peptide toxin families from the snail venoms are known to interact with potassium channels. We report the purification, synthesis, and characterization of κM-conotoxin RIIIJ from the venom of a fish-h...

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Bibliographic Details
Main Authors: Chen, Ping, Dendorfer, Andreas, Finol-Urdaneta, Rocio K., Terlau, Heinrich, Olivera, Baldomero M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865319/
https://ncbi.nlm.nih.gov/pubmed/20220134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068486
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