Dual Roles of Smad Proteins in the Conversion from Myoblasts to Osteoblastic Cells by Bone Morphogenetic Proteins

Bone morphogenetic proteins (BMPs) induce ectopic bone formation in muscle tissue in vivo and convert myoblasts such that they differentiate into osteoblastic cells in vitro. We report here that constitutively active Smad1 induced osteoblastic differentiation of C2C12 myoblasts in cooperation with S...

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Библиографические подробности
Главные авторы: Nojima, Junya, Kanomata, Kazuhiro, Takada, Yumi, Fukuda, Toru, Kokabu, Shoichiro, Ohte, Satoshi, Takada, Takatora, Tsukui, Tohru, Yamamoto, Takamasa S., Sasanuma, Hiroki, Yoneyama, Katsumi, Ueno, Naoto, Okazaki, Yasushi, Kamijo, Ryutaro, Yoda, Tetsuya, Katagiri, Takenobu
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865305/
https://ncbi.nlm.nih.gov/pubmed/20231279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028019
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