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Proton-driven Assembly of the Rous Sarcoma Virus Capsid Protein Results in the Formation of Icosahedral Particles

In a mature and infectious retroviral particle, the capsid protein (CA) forms a shell surrounding the genomic RNA and the replicative machinery of the virus. The irregular nature of this capsid shell precludes direct atomic resolution structural analysis. CA hexamers and pentamers are the fundamenta...

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Autores principales: Hyun, Jae-Kyung, Radjainia, Mazdak, Kingston, Richard L., Mitra, Alok K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865289/
https://ncbi.nlm.nih.gov/pubmed/20228062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108209
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