Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis.

Rheumatoid arthritis is an autoimmune disease characterized by T-cell infiltration of the synovium of joints. Analysis of the phenotype and antigen specificity of the infiltrating cells may thus provide insight into the pathogenesis of rheumatoid arthritis. T cells were cloned with interleukin 2, a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Londei, M, Savill, C M, Verhoef, A, Brennan, F, Leech, Z A, Duance, V, Maini, R N, Feldmann, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2463633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.636
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