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Optimized Cannula Design and Placement for Convection-enhanced Delivery in Rat Striatum

The stereotactic delivery of therapeutic agents into brain has been problematic because of reflux and leakage of the delivered agent. Good distribution of infusates by convection-enhanced delivery (CED) depends very much on cannula design, precise cannula placement and infusion rates. We have recent...

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Bibliografiske detaljer
Main Authors: Yin, Dali, Forsayeth, John, Bankiewicz, Krystof S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865230/
https://ncbi.nlm.nih.gov/pubmed/20026357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2009.12.008
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