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Apoptosis of activated CD4+ and CD8+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction

A central unresolved issue in hepatitis C virus (HCV) infection is how the virus establishes chronic infection. Recent studies suggest that the liver microenvironment leads to apoptosis of activated T cells, which may be involved in the tolerance to liver allograft. Here, We report that murine hepat...

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Detalhes bibliográficos
Main Authors: Iken, Khadija, Huang, Lin, Bekele, Hewan, Schmidt, Emmett V., Koziel, Margaret James
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865190/
https://ncbi.nlm.nih.gov/pubmed/16336987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.11.017
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