MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques

The importance of a broad CD8-T lymphocyte (CD8-TL) immune response to HIV is unknown. Ex vivo measurements of immunological activity directed at a limited number of defined epitopes provide an incomplete portrait of the actual immune response. Here we examined viral loads in SIV-infected MHC homozy...

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Detalhes bibliográficos
Main Authors: O'Connor, Shelby L., Lhost, Jennifer J., Becker, Ericka A., Detmer, Ann M., Johnson, Randall C., MacNair, Caitlin E., Wiseman, Roger W., Karl, Julie A., Greene, Justin M., Burwitz, Benjamin J., Bimber, Benjamin N., Lank, Simon M., Tuscher, Jennifer J., Mee, Edward T., Rose, Nicola J., Desrosiers, Ronald C., Hughes, Austin L., Friedrich, Thomas C., Carrington, Mary, O'Connor, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865159/
https://ncbi.nlm.nih.gov/pubmed/20375000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000524
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