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Targeted drug delivery into reversibly injured myocardium with silica nanoparticles: surface functionalization, natural biodistribution, and acute toxicity

The clinical outcome of patients with ischemic heart disease can be significantly improved with the implementation of targeted drug delivery into the ischemic myocardium. In this paper, we present our original findings relevant to the problem of therapeutic heart targeting with use of nanoparticles....

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Main Authors: Galagudza, Michael M, Korolev, Dmitry V, Sonin, Dmitry L, Postnov, Viktor N, Papayan, Garry V, Uskov, Ivan S, Belozertseva, Anastasia V, Shlyakhto, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865018/
https://ncbi.nlm.nih.gov/pubmed/20463939
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