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Magnetic nanoformulation of azidothymidine 5’-triphosphate for targeted delivery across the blood–brain barrier

Despite significant advances in highly active antiretroviral therapy (HAART), the prevalence of neuroAIDS remains high. This is mainly attributed to inability of antiretroviral therapy (ART) to cross the blood–brain barrier (BBB), thus resulting in insufficient drug concentration within the brain. T...

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Hlavní autoři: Saiyed, Zainulabedin M, Gandhi, Nimisha H, Nair, Madhavan PN
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865010/
https://ncbi.nlm.nih.gov/pubmed/20463931
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