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E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.

The E2 open reading frame (ORF) of bovine papillomavirus type 1 (BPV-1) encodes positive- and negative-acting factors that regulate viral gene expression. The full-length ORF encodes a transactivator, and two transcriptional repressors are expressed from the 3' half of the ORF. Previous analysis has...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: McBride, A A, Byrne, J C, Howley, P M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.510
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