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Effect of Common Buffers and Heterocyclic Ligands on the Binding of Cu(II) at the Multimetal Binding Site in Human Serum Albumin

Visible-range circular dichroism titrations were used to study Cu(II) binding properties of Multimetal Binding Site (MBS) of Human Serum Albumin (HSA). The formation of ternary MBS-Cu(II)-Buffer complexes at pH 7.4 was positively verified for sodium phosphate, Tris, and Hepes, the three most common...

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Autors principals: Sokołowska, Magdalena, Pawlas, Krystyna, Bal, Wojciech
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864911/
https://ncbi.nlm.nih.gov/pubmed/20467459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/725153
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