Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase.

3-Hydroxyaspartic acid and 3-hydroxyasparagine are two rare amino acids that are present in domains homologous to the epidermal growth factor precursor in vitamin K-dependent plasma proteins as well as in proteins that do not require vitamin K for normal biosynthesis. They are formed by posttranslat...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Stenflo, J, Holme, E, Lindstedt, S, Chandramouli, N, Huang, L H, Tam, J P, Merrifield, R B
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.444
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