Substance P in Polymicrobial Sepsis: Molecular Fingerprint of Lung Injury in Preprotachykinin-A(−/−) Mice

Deletion of mouse preprotachykinin-A (PPTA), which encodes mainly for neuropeptide substance P, has been shown to protect against lung injury and mortality in sepsis. This study explored microarray-based differential gene expression profiles in mouse lung tissue 8 h after inducing microbial sepsis a...

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Autors principals: Hegde, Akhil, Tamizhselvi, Ramasamy, Manikandan, Jayapal, Melendez, Alirio J, Moochhala, Shabbir M, Bhatia, Madhav
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864813/
https://ncbi.nlm.nih.gov/pubmed/20454520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00166
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