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Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12
Phosphodiesterase PDE12 is a medically important esterase-family member that hydrolyzes 2′–5′-linked oligoadenylates (2-5A), which are involved in the regulation of biological processes related to the antiviral and antitumour activity that can be induced by interferons. Here, cloning, purification a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864682/ https://ncbi.nlm.nih.gov/pubmed/20445249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110008766 |
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