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Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12

Phosphodiesterase PDE12 is a medically important esterase-family member that hydrolyzes 2′–5′-linked oligoadenylates (2-5A), which are involved in the regulation of biological processes related to the antiviral and antitumour activity that can be induced by interferons. Here, cloning, purification a...

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Detalhes bibliográficos
Main Authors: Kohno, Tetsuya, Yamaguchi, Hiroto, Hakoshima, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864682/
https://ncbi.nlm.nih.gov/pubmed/20445249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110008766
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