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Structural Basis for the Modulation of CDK-Dependent/Independent Activity of Cyclin D1

D-type cyclins are key regulators of the cell division cycle. In association with Cyclin Dependent Kinases (CDK) 2/4/6, they control the G(1)/S-phase transition in part by phosphorylation and inactivation of tumor suppressor of retinoblastoma family. Defective regulation of the G(1)/S transition is...

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Bibliografische gegevens
Hoofdauteurs: Ferrer, Jean-Luc, Dupuy, Jérôme, Borel, Franck, Jacquamet, Lilian, Noel, Joseph P., Dulic, Vjekoslav
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864588/
https://ncbi.nlm.nih.gov/pubmed/17172845
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